Nicotinamide adenine dinucleotide (NAD+) is a crucial coenzyme found in all living cells, playing a vital role in metabolic processes and energy production. It exists in two forms: NAD+ and its reduced form, NADH, and is essential for the functioning of enzymes involved in redox reactions, which are critical for converting nutrients into energy. NAD+ acts as a carrier for electrons in cellular respiration, facilitating the production of adenosine triphosphate (ATP), the primary energy currency of the cell. Beyond its role in energy metabolism, NAD+ is also involved in various other cellular processes, including DNA repair, regulation of gene expression, and cell signaling. It is a key substrate for sirtuins, a family of proteins that are implicated in aging and longevity, further highlighting its importance in maintaining cellular health.
Nicotinamide Adenine Dinucleotide
CAS Number: 53-84-9
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Nicotinamide Adenine Dinucleotide
- Energy Production: NAD+ is essential for converting food into energy through cellular respiration. It acts as a coenzyme in the electron transport chain, facilitating the production of ATP, which powers cellular functions.
- DNA Repair: NAD+ plays a critical role in DNA repair mechanisms. It helps activate enzymes like poly(ADP-ribose) polymerases (PARPs), which are involved in repairing damaged DNA, thereby supporting cellular health and longevity.
- Regulation of Sirtuins: NAD+ is a key substrate for sirtuins, a group of proteins that regulate various biological processes, including aging, inflammation, and metabolism. By activating sirtuins, NAD+ may help promote healthy aging and improve metabolic function.
